KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK2
All Species:
14.24
Human Site:
S286
Identified Species:
31.33
UniProt:
Q8N568
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N568
NP_001035350.2
766
83612
S286
D
D
F
V
L
D
H
S
E
C
R
V
L
K
S
Chimpanzee
Pan troglodytes
XP_001150968
766
83601
S286
D
D
F
V
L
D
H
S
E
C
R
V
L
K
S
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
Y303
S
R
S
S
A
V
K
Y
S
G
S
K
S
P
G
Dog
Lupus familis
XP_539760
862
93767
Y303
S
R
S
S
A
V
K
Y
S
G
S
K
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGN3
756
82960
S285
D
D
F
V
L
D
H
S
E
C
R
V
L
K
S
Rat
Rattus norvegicus
Q5MPA9
767
83998
K301
Y
S
R
A
S
A
A
K
Y
S
G
S
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511279
630
68724
V186
R
S
K
S
P
A
S
V
N
G
T
P
S
S
Q
Chicken
Gallus gallus
XP_420439
761
82932
S284
D
D
F
V
L
D
H
S
E
C
R
V
M
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139259
791
87409
C291
S
T
A
F
I
T
E
C
Q
V
I
K
S
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394386
670
74883
Y226
S
G
A
V
R
K
V
Y
T
L
S
G
Q
Q
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
L217
A
H
S
F
E
Q
V
L
T
D
I
T
E
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
81.9
N.A.
93.4
92.6
N.A.
71
84.5
N.A.
71.5
N.A.
N.A.
39.5
N.A.
48.6
Protein Similarity:
100
99.4
97
83.9
N.A.
95.4
95
N.A.
75.7
89.9
N.A.
82.4
N.A.
N.A.
57
N.A.
62.1
P-Site Identity:
100
100
0
0
N.A.
100
0
N.A.
0
93.3
N.A.
0
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
0
0
N.A.
100
0
N.A.
0
100
N.A.
13.3
N.A.
N.A.
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
10
19
19
10
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
37
0
0
0
0
0
% C
% Asp:
37
37
0
0
0
37
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
37
0
0
0
10
0
0
% E
% Phe:
0
0
37
19
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
28
10
10
0
0
19
% G
% His:
0
10
0
0
0
0
37
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
10
% I
% Lys:
0
0
10
0
0
10
19
10
0
0
0
28
0
37
0
% K
% Leu:
0
0
0
0
37
0
0
10
0
10
0
0
28
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
10
0
19
10
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
0
0
10
10
10
% Q
% Arg:
10
19
10
0
10
0
0
0
0
0
37
0
10
0
0
% R
% Ser:
37
19
28
28
10
0
10
37
19
10
28
10
37
28
37
% S
% Thr:
0
10
0
0
0
10
0
0
19
0
10
10
0
0
0
% T
% Val:
0
0
0
46
0
19
19
10
0
10
0
37
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
28
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _